Predictors of hospital-acquired bacterial and fungal superinfections in COVID-19: a prospective observational study.

ABSTRACT:

Background

Bacterial and fungal superinfections may complicate the course of hospitalized patients with COVID-19.

Objectives

To identify predictors of superinfections in COVID-19.

Methods

Prospective, observational study including patients with COVID-19 consecutively admitted to the University Hospital of Pisa, Italy, between 4 March and 30 April 2020. Clinical data and outcomes were registered. Superinfection was defined as a bacterial or fungal infection that occurred ≥48 h after hospital admission. A multivariate analysis was performed to identify factors independently associated with superinfections.

Results

Overall, 315 patients with COVID-19 were hospitalized and 109 episodes of superinfections were documented in 69 (21.9%) patients. The median time from

SUBMITTER: Falcone M 

PROVIDER: S-EPMC7799007 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature