Excess burden of age-associated comorbidities among people living with HIV in British Columbia, Canada: a population-based cohort study.

ABSTRACT:

Objectives

As people living with HIV (PLWH) live longer, morbidity and mortality from non-AIDS comorbidities have emerged as major concerns. Our objective was to compare prevalence trends and age at diagnosis of nine chronic age-associated comorbidities between individuals living with and without HIV.

Design and setting

This population-based cohort study used longitudinal cohort data from all diagnosed antiretroviral-treated PLWH and 1:4 age-sex-matched HIV-negative individuals in British Columbia, Canada.

Participants

The study included 8031 antiretroviral-treated PLWH and 32 124 HIV-negative controls (median age 40 years, 82% men). Eligible participants were ≥19 years old and followed for ≥1 year during 2000 to 2012.

Primary and secondary outcome measures

The

SUBMITTER: Nanditha NGA 

PROVIDER: S-EPMC7799128 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature