Cohort profile: a multicentre prospective validation cohort of the Chinese Acute-on-Chronic Liver Failure (CATCH-LIFE) study.

ABSTRACT:

Purpose

Acute-on-chronic liver failure (ACLF) is a clinical syndrome with high short-term mortality, unclear mechanism and controversial diagnosis criteria. The Chinese Acute-on-Chronic Liver Failure (CATCH-LIFE) study has been conducted in China to fill the gaps. In the first phase (the CATCH-LIFE investigation cohort), 2600 patients were continuously recruited from 14 national nationwide liver centres from 12 different provinces of China in 2015-2016, and a series of important results were obtained. To validate the preliminary results, we designed and conducted this multicentre prospective observational cohort (the CATCH-LIFE validation cohort).

Participants

Patients diagnosed with chronic liver disease and hospitalised for acute decompensation (AD) or acute liver injure w

SUBMITTER: Qiao L 

PROVIDER: S-EPMC7799133 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature