Chip-Scale Angle-Selective Imager for In Vivo Microscopic Cancer Detection.

ABSTRACT: We present an image sensor incorporating angle-selective gratings for resolution enhancement in contact imaging applications. Optical structures designed in the CMOS metal layers above each photodiode form the angle-selective gratings that limit the sensor angle of view to ±18 ^°, rejecting background light and deblurring the image. The imager is based on a high-gain capacitive transimpedance amplifier pixel using a custom 11fF MOM capacitor, achieving [Formula: see text] sensitivity. The pixel includes a leakage current minimization circuit to remove signal-dependent reset switch leakage and the corresponding dark current is [Formula: see text]. The resulting 4.7 mm by 2.25 mm sensor (80 by 36 pixels) is designed specifically for intraoperative cancer imaging in order to solve t

SUBMITTER: Papageorgiou EP 

PROVIDER: S-EPMC7800072 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature