The prevalence of cardiac autonomic neuropathy in prediabetes: a systematic review.

ABSTRACT:

Aims/hypothesis

Cardiac autonomic neuropathy (CAN) is independently associated with silent myocardial ischaemia, major cardiovascular events, myocardial dysfunction and cardiovascular mortality. Several studies have highlighted the increased prevalence of CAN in prediabetes (impaired glucose tolerance and/or impaired fasting glucose). Considering the exponential rise of prediabetes, we aimed to determine the prevalence of CAN through a systematic literature review.

Methods

This systematic review was registered with PROSPERO (CRD42019125447). An electronic literature search was performed using MEDLINE, EMBASE, PubMed, Web of Science, Scopus and Cochrane databases. Published full text, English language articles that provide CAN prevalence data of studies in individuals with pr

SUBMITTER: Eleftheriadou A 

PROVIDER: S-EPMC7801295 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature