A novel quantitative and reference-free ultrasound analysis to discriminate different concentrations of bone mineral content.

ABSTRACT: Bone fracture is a continuous process, during which bone mineral matrix evolves leading to an increase in hydroxyapatite and calcium carbonate content. Currently, no gold standard methods are available for a quantitative assessment of bone fracture healing. Moreover, the available tools do not provide information on bone composition. Whereby, there is a need for objective and non-invasive methods to monitor the evolution of bone mineral content. In general, ultrasound can guarantee a quantitative characterization of tissues. However, previous studies required measurements on reference samples. In this paper we propose a novel and reference-free parameter, based on the entropy of the phase signal calculated from the backscattered data in combination with amplitude information, to also consi

SUBMITTER: Sorriento A 

PROVIDER: S-EPMC7801603 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature