Effectiveness of Bath Wipes After Hematopoietic Cell Transplantation: A Randomized Trial.

ABSTRACT: Objective: Bacteremia is a leading cause of morbidity and mortality in children undergoing hematopoietic cell transplantation (HCT). Infections of vancomycin-resistant enterococci (VRE) and multidrug resistant (MDR) gram-negative rods (GNRs) are common in this population. Our objective was to assess whether experimental bath wipes containing silver were more effective than standard bath wipes containing soap at reducing skin colonization by VRE and MDR GNRs, and nonmucosal barrier injury bacteremia. Study Design: Patients undergoing autologous or allogeneic HCT in a tertiary referral center were randomized to receive experimental or standard bath wipes for 60 days post-HCT. Skin swabs were collected at baseline, discharge, and day +60 post-HCT. The rate of VRE colonization wa

SUBMITTER: Kjellin M 

PROVIDER: S-EPMC7802025 | biostudies-literature | 2020 Nov/Dec

REPOSITORIES: biostudies-literature