Prediction of Cardiovascular Events by Type I Central Systolic Blood Pressure: A Prospective Study.

ABSTRACT: Compared with brachial blood pressure (BP), central systolic BP (SBP) can provide a better indication of the hemodynamic strain inflicted on target organs, but it is unclear whether this translates into improved cardiovascular risk stratification. We aimed to assess which of central or brachial BP best predicts cardiovascular risk and to identify the central SBP threshold associated with increased risk of future cardiovascular events. This study included 13 461 participants of CARTaGENE with available central BP and follow-up data from administrative databases but without cardiovascular disease or antihypertensive medication. Central BP was estimated by radial artery tonometry, calibrated for brachial SBP and diastolic BP (type I), and a generalized transfer function (SphygmoCor). The outc

SUBMITTER: Lamarche F 

PROVIDER: S-EPMC7803443 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature