Ontology highlight
ABSTRACT:
SUBMITTER: Jung JH
PROVIDER: S-EPMC7804108 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Scientific reports 20210112 1
Isolation of pure extracellular vesicles (EVs), especially from blood, has been a major challenge in the field of EV research. The presence of lipoproteins and soluble proteins often hinders the isolation of high purity EVs upon utilization of conventional separation methods. To circumvent such problems, we designed a single-step dual size-exclusion chromatography (dSEC) column for effective isolation of highly pure EVs from bone marrow derived human plasma. With an aim to select appropriate col ...[more]