Genome diversity in Ukraine.

ABSTRACT:

Background

The main goal of this collaborative effort is to provide genome-wide data for the previously underrepresented population in Eastern Europe, and to provide cross-validation of the data from genome sequences and genotypes of the same individuals acquired by different technologies. We collected 97 genome-grade DNA samples from consented individuals representing major regions of Ukraine that were consented for public data release. BGISEQ-500 sequence data and genotypes by an Illumina GWAS chip were cross-validated on multiple samples and additionally referenced to 1 sample that has been resequenced by Illumina NovaSeq6000 S4 at high coverage.

Results

The genome data have been searched for genomic variation represented in this population, and a number of variants have

SUBMITTER: Oleksyk TK 

PROVIDER: S-EPMC7804371 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature