Contralesional functional network reorganization of the insular cortex in diffuse low-grade glioma patients.

ABSTRACT: Diffuse low-grade gliomas (DLGGs) growing on the insular lobe induce contralesional hemispheric insular lobe compensation of damaged functioning by increasing cortical volumes. However, it remains unclear how functional networks are altered in patients with insular lobe DLGGs during functional compensation. Thirty-five patients with insular DLGGs were classified into the left (insL, n = 16) and right groups (insR, n = 19), and 33 healthy subjects were included in the control group. Resting state functional magnetic resonance imaging was used to generate functional connectivity (FC), and network topological properties were evaluated using graph theoretical analysis based on FC matrices. Network-based statistics were applied to compare differences in the FC matrices. A false discovery rate w

SUBMITTER: Fang S 

PROVIDER: S-EPMC7804949 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature