Prognostic value of early leukocyte fluctuations for recovery from traumatic spinal cord injury.

ABSTRACT:

Background

Acute traumatic spinal cord injury (SCI) induces a systemic immune response involving circulating white blood cells (WBCs). How this response is influenced by overall trauma severity, the neurological level of injury and/or correlates with patient outcomes is poorly understood. The objective of this study was to identify relationships between early changes in circulating WBCs, injury characteristics and long-term patient outcomes in individuals with traumatic SCI.

Methods

We retrospectively analysed data from 161 SCI patients admitted to Brisbane's Princess Alexandra Hospital (exploration cohort). Logistic regression models in conjunction with receiver operating characteristic (ROC) analyses were used to assess the strength of specific links between the WBC respon

SUBMITTER: Jogia T 

PROVIDER: S-EPMC7805435 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature