DALIA- a comprehensive resource of Disease Alleles in Arab population.

ABSTRACT: The Arab population encompasses over 420 million people characterized by genetic admixture and a consequent rich genetic diversity. A number of genetic diseases have been reported for the first time from the population. Additionally a high prevalence of some genetic diseases including autosomal recessive disorders such as hemoglobinopathies and familial mediterranean fever have been found in the population and across the region. There is a paucity of databases cataloguing genetic variants of clinical relevance from the population. The availability of such a catalog could have implications in precise diagnosis, genetic epidemiology and prevention of disease. To fill in the gap, we have compiled DALIA, a comprehensive compendium of genetic variants reported in literature and implicated in ge

SUBMITTER: Vatsyayan A 

PROVIDER: S-EPMC7806169 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature