Enantioselective Synthesis of Alkyl Allyl Ethers via Palladium-Catalyzed Redox-Relay Heck Alkenylation of O-Alkyl Enol Ethers.

ABSTRACT: Herein we report a transformation that generates an array of enantiomerically enriched, alkyl allyl ethers. Cyclic, acyclic, and heteroatom-bearing alkenyl triflates undergo an enantioselective, palladium-catalyzed C-C bond formation with diverse acyclic O-alkyl enol ethers in good yields and excellent enantioselectivities.

SUBMITTER: Prater MB 

PROVIDER: S-EPMC7806183 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature