Left atrial appendage closure in patients with chronic kidney disease: results from the German multicentre LAARGE registry.

ABSTRACT:

Objectives

Chronic kidney disease (CKD) is associated with an increased complication rate after cardiac interventions. Although CKD has a high prevalence among atrial fibrillation patients, the impact of CKD on periprocedural complications and the outcome after an interventional left atrial appendage closure (LAAC) is unclear. The present study, therefore, aimed to investigate whether CKD influences the procedure's effectiveness and safety.

Methods

LAARGE is a prospective, non-randomised registry. LAAC was conducted with different standard commercial devices, and the follow-up period was one year. CKD was defined by an eGFR < 60 mL/min/1.73 m², and subgroups were further analysed (i.e. eGFR < 15, 15-29, and 30-59 mL/min/1.73 m², respectively).

Result

SUBMITTER: Fastner C 

PROVIDER: S-EPMC7806558 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature