An observational study on the effect of hypercholesterolemia developed after living donor liver transplantation on cardiac event and graft failure.

ABSTRACT: This study sought to evaluate the association between newly-developed significant hypercholesterolemia within one year following living donor liver transplantation (LDLT) and long term outcomes in light of cardiovascular events and graft failure. From October 2003 to July 2017, 877 LDLT recipients were stratified according to development of significant hypercholesterolemia within one year following LDLT. The primary outcome was occurrence of a major adverse cardiac event (MACE), defined as a composite of cardiac death, myocardial infarction, and coronary revascularization after LDLT. The incidence of graft failure, defined as all-cause death or retransplantation, was also compared. A total of 113 (12.9%) recipients developed significant hypercholesterolemia within one year. The differences

SUBMITTER: Park J 

PROVIDER: S-EPMC7806822 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature