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Hydroxychloroquine in the treatment of outpatients with mildly symptomatic COVID-19: a multi-center observational study.


ABSTRACT:

Background

Hydroxychloroquine has not been associated with improved survival among hospitalized COVID-19 patients in the majority of observational studies and similarly was not identified as an effective prophylaxis following exposure in a prospective randomized trial. We aimed to explore the role of hydroxychloroquine therapy in mildly symptomatic patients diagnosed in the outpatient setting.

Methods

We examined the association between outpatient hydroxychloroquine exposure and the subsequent progression of disease among mildly symptomatic non-hospitalized patients with documented SARS-CoV-2 infection. The primary outcome assessed was requirement of hospitalization. Data was obtained from a retrospective review of electronic health records within a New Jersey USA multi-hosp

SUBMITTER: Ip A 

PROVIDER: S-EPMC7807228 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature