Antibiotic resistance gene sharing networks and the effect of dietary nutritional content on the canine and feline gut resistome.

ABSTRACT:

Background

As one of the most densely populated microbial communities on Earth, the gut microbiota serves as an important reservoir of antibiotic resistance genes (ARGs), referred to as the gut resistome. Here, we investigated the association of dietary nutritional content with gut ARG diversity and composition, using publicly available shotgun metagenomic sequence data generated from canine and feline fecal samples. Also, based on network theory, we explored ARG-sharing patterns between gut bacterial genera by identifying the linkage structure between metagenomic assemblies and their functional genes obtained from the same data.

Results

In both canine and feline gut microbiota, an increase in protein and a reduction in carbohydrate in the diet were associated with increased

SUBMITTER: Kim Y 

PROVIDER: S-EPMC7807453 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature