Multi-center evaluation of dose conformity in stereotactic body radiotherapy.

ABSTRACT:

Background and purpose

Stereotactic body radiotherapy (SBRT) is an emerging technique for treating oligometastases, but limited data is available on what plan quality is achievable for a range of modalities and clinical sites.

Methods

SBRT plans for lung, spine, bone, adrenal, liver and node sites from 17 participating centers were reviewed. Centers used various delivery techniques including static and rotational intensity-modulation and multiple non-coplanar beams. Plans were split into lung and other body sites and evaluated with different plan quality metrics, including two which are independent of target coverage; "prescription dose spillage" (PDS) and "modified gradient index" (MGI). These were compared to constraints from the ROSEL and RTOG 0813 clinical trials.

Res

SUBMITTER: Lee J 

PROVIDER: S-EPMC7807546 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature