Design, fabrication, and validation of patient-specific electron tissue compensators for postmastectomy radiation therapy.

ABSTRACT:

Background and purpose

Postmastectomy radiotherapy (PMRT) is complex to plan and deliver, but could be improved with 3D-printed, patient-specific electron tissue compensators. The purposes of this study were to develop an algorithm to design patient-specific compensators that achieve clinical goals, to 3D-print the planned compensators, and validate calculated dose distributions with film and thermoluminescent dosimeter (TLD) measurements in 3D-printed phantoms of PMRT patients.

Materials and methods

An iterative algorithm was developed to design compensators corresponding to single-field, single-energy electron plans for PMRT patients. The 3D-printable compensators were designed to fit into the electron aperture, with cerrobend poured around it. For a sample of eight patien

SUBMITTER: Craft DF 

PROVIDER: S-EPMC7807570 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature