Breast-shape changes during radiation therapy after breast-conserving surgery.

ABSTRACT:

Background & purpose

With the introduction of more conformal techniques for breast cancer radiation therapy (RT), motion management is becoming increasingly important. We studied the breast-shape variability during RT after breast-conserving surgery (BCS).

Materials & methods

Planning computed tomography (CT) and follow-up cone-beam CT (CBCT) scans were available for 71 fractions of 17 patients undergoing RT after BCS. First, the CT and the CBCT scans were registered on bones. Subsequently, breast-contour data were generated. The CBCT contours were analyzed in 3D in terms of deviations (mean and standard deviation) relative to the contour of the CT scan for the upper medial, lower medial, upper lateral, and lower lateral breast quadrants, and the axilla.

Results

Regio

SUBMITTER: Alderliesten T 

PROVIDER: S-EPMC7807602 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature