Furanocoumarin with Phytotoxic Activity from the Leaves of Amyris elemifera (Rutaceae).

ABSTRACT: Bioassay-guided fractionation of the ethyl acetate extract of Amyris elemifera leaves was carried out to identify phytotoxic and antifungal constituents. A novel phytotoxic furanocoumarin 8-(3-methylbut-2-enyloxy)-marmesin acetate (1) and its deacyl analog 8-(3-methylbut-2-enyloxy)-marmesin (2) were isolated. The X-ray crystal structure determination is reported for the first time for 1. Both 1 and 2 have the S configuration at C-2' based on X-ray crystallographic data. Both these compounds inhibited the growth of the dicot Lactuca sativa (lettuce) and the monocot Agrostis stolonifera with a more pronounced inhibitory effect on the monocots at 330 μM by 1. In Lemna paucicostata Hegelm phytotoxicity bioassay, the IC₅

SUBMITTER: Meepagala KM 

PROVIDER: S-EPMC7807802 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature