Evaluating the impact of cone-beam computed tomography scatter mitigation strategies on radiotherapy dose calculation accuracy.

ABSTRACT:

Background and purpose

The scatter induced image quality degradation of cone-beam computed tomography (CBCT) prevents more advanced applications in radiotherapy. We evaluated the dose calculation accuracy on CBCT of various disease sites using different scatter mitigation strategies.

Materials and methods

CBCT scans of two patient cohorts (C1, C2) were reconstructed using a uniform (USC) and an iterative scatter correction (ISC) method, combined with an anti-scatter grid (ASG). Head and neck (H&N), lung, pelvic region, and prostate patients were included. To achieve a high accuracy Hounsfield unit and physical density calibrations were performed. The dose distributions of the original treatment plans were analyzed with the γ evaluation method using criteria of 1%/2 mm using

SUBMITTER: Schroder L 

PROVIDER: S-EPMC7807872 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature