A treatment planning study of combined carbon ion-beam plus photon intensity-modulated radiotherapy.

ABSTRACT:

Background and purpose

Combined photon intensity-modulated radiotherapy (IMRT) and sequential dose-escalated carbon ion beam therapy (IBT) is a technically advanced treatment option for head and neck malignancies. We proposed and evaluated an integrated planning strategy as opposed to an established and largely separated planning workflow.

Materials and methods

Ten patients with representative malignancies of the head and neck region underwent combined carbon-photon radiotherapy (RT) in our facilities. Clinical plans were created according to the separated workflow with independent optimization stages for both modalities. Experimental plans incorporated the existing carbon IBT dose distribution into the optimization stage of a step-and-shoot photon IMRT (bias dose planning).

SUBMITTER: Schuppert C 

PROVIDER: S-EPMC7807875 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature