Feasibility of using a novel automatic cardiac segmentation algorithm in the clinical routine of lung cancer patients.

ABSTRACT: Incidental radiation exposure to the heart during lung cancer radiotherapy is associated with radiation-induced heart disease and increased rates of mortality. By considering the respiratory-induced motion of the heart it is possible to create a radiotherapy plan that results in a lower overall cardiac dose. This approach is challenging using current clinical practices: manual contouring of the heart is time consuming, and subject to inter- and intra-observer variability. In this work, we investigate the feasibility of our previously developed, atlas-based, automatic heart segmentation tool to delineate the heart in four-dimensional x-ray computed tomography (4D-CT) images. We used a dataset comprising 19 patients receiving radiotherapy for lung cancer, with 4D-CT imaging acquired at 10 re

SUBMITTER: Finnegan RN 

PROVIDER: S-EPMC7808597 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature