Predicting in-hospital mortality from Coronavirus Disease 2019: A simple validated app for clinical use.

ABSTRACT:

Backgrounds

Validated tools for predicting individual in-hospital mortality of COVID-19 are lacking. We aimed to develop and to validate a simple clinical prediction rule for early identification of in-hospital mortality of patients with COVID-19.

Methods and findings

We enrolled 2191 consecutive hospitalized patients with COVID-19 from three Italian dedicated units (derivation cohort: 1810 consecutive patients from Bergamo and Pavia units; validation cohort: 381 consecutive patients from Rome unit). The outcome was in-hospital mortality. Fine and Gray competing risks multivariate model (with discharge as a competing event) was used to develop a prediction rule for in-hospital mortality. Discrimination and calibration were assessed by the area under the receiver operating ch

SUBMITTER: Magro B 

PROVIDER: S-EPMC7808616 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature