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High-resolution analysis of baculovirus-induced host manipulation in the domestic silkworm, Bombyx mori.

ABSTRACT: Many parasites manipulate host behaviour to enhance their transmission. Baculoviruses induce enhanced locomotory activity (ELA) combined with subsequent climbing behaviour in lepidopteran larvae, which facilitates viral dispersal. However, the mechanisms underlying host manipulation system are largely unknown. Previously, larval locomotion during ELA was summarized as the distance travelled for a few minutes at several time points, which are unlikely to characterize ELA precisely, as ELA typically persists for several hours. In this study, we modified a recently developed method using time-lapse recording to characterize locomotion of Bombyx mori larvae infected with Bombyx mori nucleopolyhedrovirus (BmNPV) for 24 h at 3 s resolution.

SUBMITTER: Hikida H

PROVIDER: S-EPMC7808863 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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High-resolution analysis of baculovirus-induced host manipulation in the domestic silkworm, Bombyx mori.

Hikida Hiroyuki H Katsuma Susumu S

Parasitology 20201015 1

Many parasites manipulate host behaviour to enhance their transmission. Baculoviruses induce enhanced locomotory activity (ELA) combined with subsequent climbing behaviour in lepidopteran larvae, which facilitates viral dispersal. However, the mechanisms underlying host manipulation system are largely unknown. Previously, larval locomotion during ELA was summarized as the distance travelled for a few minutes at several time points, which are unlikely to characterize ELA precisely, as ELA typical ...[more]

PMID: 33054893

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