The Effect of Exercise During Pregnancy on Maternal and Offspring Vascular Outcomes: a Pilot Study.

ABSTRACT: The aim of this pilot study is to obtain estimates for the change in maternal cerebrovascular (primary) and offspring vascular structure (secondary) during healthy pregnancy that includes structured exercise. Eighteen pregnant women self-assigned to a moderate-intensity aerobic exercise intervention or a control group. Maternal cerebral blood flow (CBF) at the middle cerebral artery, cerebro- and peripheral-vascular function was assessed at the end of each trimester. Offspring carotid artery intima-media thickness (IMT) was measured within 12 weeks of birth. For exploratory purposes, we performed statistical analysis to provide estimates of the change for primary and secondary outcome variables. Maternal CBF reduced (- 8 cm s^-1 [- 14 to - 2]) with evidence of change to cerebral

SUBMITTER: Brislane A 

PROVIDER: S-EPMC7808996 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature