Clinical characteristics and overall survival nomogram of second primary malignancies after prostate cancer, a SEER population-based study.

ABSTRACT: Prostate cancer (PCa) is the most prevalent cancer among males and the survival period of PCa has been significantly extended. However, the probability of suffering from second primary malignancies (SPMs) has also increased. Therefore, we downloaded SPM samples from the SEER database and then retrospectively analyzed the general characteristics of 34,891 PCa patients diagnosed between 2000 and 2016. After excluding cases with unknown clinical information, 2203 patients were used to construct and validate the overall survival (OS) nomogram of SPM patients after PCa. We found that approximately 3.69% of PCa patients were subsequently diagnosed with SPMs. In addition, the three most prevalent sites of SPM were respiratory and intrathoracic organs, skin, and hematopoietic system. The top three

SUBMITTER: Liu Y 

PROVIDER: S-EPMC7809269 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature