Long non-coding RNA FTX predicts a poor prognosis of human cancers: a meta-analysis.

ABSTRACT:

Background

Several studies have assessed the relationship between long non-coding RNA five prime to Xist (FTX) expression, clinicopathological features, and survival outcomes in patients with cancer with conflicting results. This meta-analysis synthesized existing data to clarify the association between FTX with cancer prognosis.

Methods

PubMed, Embase, Cochrane library, Web of Science, Chinese CNKI, and the Chinese WanFang databases were used to search for relevant studies. The role of FTX in cancers was evaluated by pooled odds ratios (ORs) and hazard ratios (HRs) with 95% confidence intervals (CIs).

Results

Eleven studies comprising 1210 participants including colorectal cancer (CRC), hepatocellular carcinoma (HCC), gastric cancer (GC), renal cell carcinoma (RCC),

SUBMITTER: Chen W 

PROVIDER: S-EPMC7809557 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature