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Association of Prolonged-Duration Chemoprophylaxis With Venous Thromboembolism in High-risk Patients With Head and Neck Cancer.


ABSTRACT:

Importance

Venous thromboembolism (VTE) is associated with substantial morbidity and is the most common factor associated with preventable death among hospitalized patients. Data from otolaryngologic studies suggest that the risk of VTE may be underestimated among high-risk patients, particularly among those undergoing oncologic procedures. The incorporation of prolonged-duration chemoprophylaxis (PDC) into preventive therapy has been associated with substantial decreases in VTE incidence among patients undergoing oncologic surgery. However, bleeding remains a major concern among otolaryngologists, and substantial variation exists in the use of thromboprophylaxis.

Objective

To assess the association between PDC and VTE in high-risk patients with head and neck cancer undergoi

SUBMITTER: Tipirneni KE 

PROVIDER: S-EPMC7809613 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature