Comparison of rectal swab, glove tip, and participant-collected stool techniques for gut microbiome sampling.

ABSTRACT:

Background

Studies of the gut microbiome are becoming increasingly important. Such studies require stool collections that can be processed or frozen in a timely manner so as not to alter the microbial content. Due to the logistical difficulties of home-based stool collection, there has been a challenge in selecting the appropriate sample collection technique and comparing results from different microbiome studies. Thus, we compared stool collection and two alternative clinic-based fecal microbiome collection techniques, including a newer glove-based collection method.

Results

We prospectively enrolled 22 adult men from our prostate cancer screening cohort SABOR (San Antonio Biomarkers of Risk for prostate cancer) in San Antonio, TX, from 8/2018 to 4/2019. A rectal swab and g

SUBMITTER: Short MI 

PROVIDER: S-EPMC7809826 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature