Effect of oral statin use on mitomycin-C augmented trabeculectomy outcomes.

ABSTRACT:

Purpose

The effect of statins on wound healing is controversial, and their effect on trabeculectomy outcomes remains unclear. This study aimed to examine the relationship between oral statin use and trabeculectomy outcomes.

Methods

Medical records of patients who underwent primary mitomycin-C augmented trabeculectomy with 2 years of follow-up were reviewed. Pre- and postoperative intraocular pressures (IOP) and numbers of medications, subconjunctival 5-fluorouracil (5-FU) injections, and bleb-needling procedures were compared between statin users and nonusers. Failure was defined as an eye that failed to achieve a 20% lowering of IOP from baseline or had an IOP > 21 mm Hg, as well as an eye that required further surgical intervention, developed hypotony, or had no light perc

SUBMITTER: Inobhas A 

PROVIDER: S-EPMC7810309 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature