Symptom heterogeneity and patient subgroup classification among US patients with post-treatment Lyme disease: an observational study.

ABSTRACT:

Objectives

To identify underlying subgroups with distinct symptom profiles, and to characterise and compare these subgroups across a range of demographic, clinical and psychosocial factors, within a heterogeneous group of patients with well-defined post-treatment Lyme disease (PTLD).

Design

A clinical case series of patents.

Setting

Participants were recruited from a single-site, Lyme disease referral clinic patient population and were evaluated by physical exam, clinical laboratory testing and standardised questionnaires.

Participants

Two hundred and twelve participants met study criteria for PTLD, with medical record-confirmed prior Lyme disease as well as current symptoms and functional impact.

Results

Exploratory factor analysis classified 30 self-re

SUBMITTER: Rebman AW 

PROVIDER: S-EPMC7812114 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature