Current and future immunotherapy approaches in ovarian cancer.
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ABSTRACT:
SUBMITTER: Demircan NC
PROVIDER: S-EPMC7812210 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Current and future immunotherapy approaches in ovarian cancer.
Demircan Nazım Can NC Boussios Stergios S Tasci Tolga T Öztürk Mehmet Akif MA
Annals of translational medicine 20201201 24
Ovarian cancer (OC) is the major cause of gynecologic cancer deaths and relapse is common despite advances in surgery and systemic chemotherapy. Therefore, novel treatments are required to improve long-term outcomes of the disease. Efficacy of immunotherapy was demonstrated in many tumors and it has been since incorporated into clinical practice for them. Although early data form preclinical studies imply that OC has an immunogenic microenvironment, immune checkpoint inhibitors (ICIs) did not pr ...[more]
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