Fitness in Young Adulthood and Long-Term Cardiac Structure and Function: The CARDIA Study.

ABSTRACT:

Objectives

This study sought to evaluate the association between early-life cardiorespiratory fitness (CRF) and measures of left ventricular (LV) structure and function in midlife.

Background

Low CRF in midlife is associated with a higher risk of heart failure. However, the unique contributions of early-life CRF toward measures of LV structure and function in middle age are not known.

Methods

CARDIA (Coronary Artery Risk Development in Young Adults) study participants with a baseline maximal treadmill test and an echocardiogram at year 25 were included. Associations among baseline CRF, CRF change, and echocardiographic LV parameters (global longitudinal strain [GLS] and global circumferential strain, E/e') were assessed using multivariable linear regression.

Result

SUBMITTER: Pandey A 

PROVIDER: S-EPMC7812548 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature