Dietary phenotype and advanced glycation end-products predict WTC-obstructive airways disease: a longitudinal observational study.

ABSTRACT:

Background

Diet is a modifier of metabolic syndrome which in turn is associated with World Trade Center obstructive airways disease (WTC-OAD). We have designed this study to (1) assess the dietary phenotype (food types, physical activity, and dietary habits) of the Fire Department of New York (FDNY) WTC-Health Program (WTC-HP) cohort and (2) quantify the association of dietary quality and its advanced glycation end product (AGE) content with the development of WTC-OAD.

Methods

WTC-OAD, defined as developing WTC-Lung Injury (WTC-LI; FEV₁ < LLN) and/or airway hyperreactivity (AHR; positive methacholine and/or positive bronchodilator response). Rapid Eating and Activity Assessment for Participants-Short Version (REAP-S) deployed on 3/1/2018 in the WTC-HP annual monit

SUBMITTER: Lam R 

PROVIDER: S-EPMC7812653 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature