Age-Related Changes in Choroidal Thickness and the Volume of Vessels and Stroma Using Swept-Source OCT and Fully Automated Algorithms.

ABSTRACT:

Purpose

To determine age-related changes in choroidal thickness and the volume of choroidal vessels and stroma using automated algorithms based on structural swept-source OCT (SS-OCT) scans.

Design

Prospective and observational study.

Participants

The study included 144 normal participants with ages ranging from 20 to 88 years.

Methods

A previously reported strategy was used to automatically segment the choroid using SS-OCT structural images. Attenuation correction was applied on B-scans to enhance the choroidal contrast and facilitate more accurate automatic segmentation of the 3-dimensional choroidal vessel and stroma. The parameters that we investigated included mean choroidal thickness (MCT), choroidal vessel volume (CVV), choroidal stroma volume (CSV), cho

SUBMITTER: Zhou H 

PROVIDER: S-EPMC7812781 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature