Unknown

Dataset Information

0

Risk Factors for Mortality, Intensive Care Unit Admission, and Bacteremia in Patients Suspected of Sepsis at the Emergency Department: A Prospective Cohort Study.


ABSTRACT:

Background

There is a clear need for a better assessment of independent risk factors for in-hospital mortality, intensive care unit admission, and bacteremia in patients presenting with suspected sepsis at the emergency department.

Methods

A prospective observational cohort study including 1690 patients was performed. Two multivariable logistic regression models were used to identify independent risk factors.

Results

Sequential organ failure assessment (SOFA) score of ?2 and serum lactate of ?2mmol/L were associated with all outcomes. Other independent risk factors were individual SOFA variables and systemic inflammatory response syndrome variables but varied per outcome. Mean arterial pressure <70 mmHg negatively impacted all outcomes.

Conclusions

These readily available measurements can help with early risk stratification and prediction of prognosis.

SUBMITTER: D'Onofrio V 

PROVIDER: S-EPMC7813192 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

Risk Factors for Mortality, Intensive Care Unit Admission, and Bacteremia in Patients Suspected of Sepsis at the Emergency Department: A Prospective Cohort Study.

D'Onofrio Valentino V   D'Onofrio Valentino V   Meersman Agnes A   Vijgen Sara S   Cartuyvels Reinoud R   Messiaen Peter P   Gyssens Inge C IC  

Open forum infectious diseases 20201228 1


<h4>Background</h4>There is a clear need for a better assessment of independent risk factors for in-hospital mortality, intensive care unit admission, and bacteremia in patients presenting with suspected sepsis at the emergency department.<h4>Methods</h4>A prospective observational cohort study including 1690 patients was performed. Two multivariable logistic regression models were used to identify independent risk factors.<h4>Results</h4>Sequential organ failure assessment (SOFA) score of ≥2 an  ...[more]

Similar Datasets

2020-01-01 | GSE119217 | GEO