Infection-related complications after common infection in association with new antibiotic prescribing in primary care: retrospective cohort study using linked electronic health records.

ABSTRACT:

Objective

Determine the association of incident antibiotic prescribing levels for common infections with infection-related complications and hospitalisations by comparing high with low prescribing general practitioner practices.

Design retrospective cohort study

Retrospective cohort study.

Data source

UK primary care records from the Clinical Practice Research Datalink (CPRD GOLD) and SAIL Databank (SAIL) linked with Hospital Episode Statistics (HES) data, including 546 CPRD, 346 CPRD-HES and 338 SAIL-HES practices.

Exposures

Initial general practice visit for one of six common infections and the proportion of antibiotic prescribing in each practice.

Main outcome measures

Incidence of infection-related complications (as recorded in general practice) or i

SUBMITTER: van Bodegraven B 

PROVIDER: S-EPMC7813359 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature