Predictive factors of posttreatment fracture by definitive radiotherapy for uterine cervical cancer.

ABSTRACT:

Purpose

Fractures are known to shorten life expectancy and worsen the quality of life. The risk of fractures after radiation therapy in cervical cancer patients is known to be multifactorial. In this study, we examined risk factors for fractures in cervical cancer patients, especially by evaluating bone densities and DVH parameters for fractured bones.

Materials and methods

For 42 patients, clinical characteristics, pretreatment CT bone densities, and radiation dose were compared between patients with and without fractures.

Results

Posttreatment fractures occurred in 25 bones among ten patients. Pretreatment CT bone densities were significantly lower in patients with fractures (P < 0.05-0.01 across sites, except for the ilium and the ischium). Although DVH parameters

SUBMITTER: Ishikawa K 

PROVIDER: S-EPMC7813741 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature