Understanding adherence to reactive treatment of asymptomatic malaria infections in The Gambia.

ABSTRACT: The impact of different types of reactive case detection and/or treatment strategies for malaria elimination depends on high coverage and participants' adherence. However, strategies to optimise adherence are limited, particularly for people with asymptomatic or no infections. As part of a cluster-randomized trial to evaluate the effect of reactive treatment in The Gambia, all residents in the compound of a diagnosed clinical malaria patient received dihydro-artemisinin-piperaquine (DP). Using a mixed method approach, we assessed which factors contribute to adherence among the contacts of malaria cases that showed no symptoms. Adherence was defined as the proportion of compound members that (1) returned all medicine bags empty and (2) self-reported (3-day) treatment completion. Among the 2

SUBMITTER: Jaiteh F 

PROVIDER: S-EPMC7813830 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature