Computational approach for the identification of putative allergens from Cucurbitaceae family members.

ABSTRACT: Certain substances referred to as allergens, induce hypersensitivity (allergic reactions) which normally are considered to be innocuous, are small in size and incite IgE response. This study was focused to predict the putative allergens from other Cucurbitaceae family members using computational approach by analyzing the already reported allergens of the same family. The four reported allergens Cuc m 1, Cuc m 2, Cuc m 3 and Citr I 2 of Cucurbitaceae family were obtained from International Union of Immunological Societies, in which three were from Cucumis melo (Muskmelon) and one from Citrullus lanatus (Watermelon) respectively. BlastP analysis reported 44 similar sequences to these allergens from other members of Cucurbitaceae family namely Cucurbita moschata, Cucur

SUBMITTER: Neeharika D 

PROVIDER: S-EPMC7813966 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature