Age-Specific Acute Changes in Carotid-Femoral Pulse Wave Velocity With Head-up Tilt.

ABSTRACT:

Background

Aortic stiffness as measured by carotid-femoral pulse wave velocity (cfPWV) is known to depend on blood pressure (BP), and this dependency may change with age. Therefore, the hydrostatic BP gradient resulting from a change in body posture may elicit a cfPWV change that is age-dependent. We aimed to analyze the relationship between BP gradient-induced by head-up body tilting-and related changes in cfPWV in individuals of varying age.

Methods

cfPWV and other hemodynamic parameters were measured in 30 healthy individuals at a head-up tilt of 0° (supine), 30°, and 60°. At each angle, the PWV gradient and resulting cfPWV were also estimated (predicted) by assuming a global nonlinear, exponential, pressure-diameter relationship characterized by a constant β0, and taking

SUBMITTER: Pucci G 

PROVIDER: S-EPMC7814224 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature