Diagnosis and treatment of Rosai-Dorfman disease of the spine: a systematic literature review.

ABSTRACT:

Purpose

To review and summarize the clinical features, diagnosis, treatment strategies, and prognosis of spinal Rosai-Dorfman disease (RDD).

Methods

RDD is also termed as sinus histiocytosis with massive lymphadenopathy. We searched the databases of PubMed, Elsevier ScienceDirect, SpringerLink, and OVID. The keywords were Rosai-Dorfman disease and spine/central nervous system. Research articles and case reports with accessibility to full texts regarding spinal RDD were eligible for the inclusion. A total of 62 articles were included, and they contained 69 cases. We extracted the information of interest and analyzed them using SPSS statistics package.

Results

The average age was 33.1 ± 18.3 years. The ratio of males to females was 1.9/1. Overall, 63 cases presented wit

SUBMITTER: Hu PP 

PROVIDER: S-EPMC7814441 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature