Modeling defibrillation benefit for survival among cardiac resynchronization therapy defibrillator recipients.

ABSTRACT:

Background

Patients with heart failure having a low expected probability of arrhythmic death may not benefit from implantable cardioverter defibrillators (ICDs).

Objective

The objective was to validate models to identify cardiac resynchronization therapy (CRT) candidates who may not require CRT devices with ICD functionality.

Methods

Heart failure (HF) patients with CRT-Ds and non-CRT ICDs from the National Cardiovascular Data Registry and others with no device from 3 separate registries and 3 heart failure trials were analyzed using multivariable Cox proportional hazards regression for survival with the Seattle Heart Failure Model (SHFM; estimates overall mortality) and the Seattle Proportional Risk Model (SPRM; estimates proportional risk of arrhythmic death).

Re

SUBMITTER: Bilchick KC 

PROVIDER: S-EPMC7814502 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature