Transcutaneous carbon dioxide pattern and trend over time in preterm infants.

ABSTRACT:

Background

Chronic lung disease remains a burden for extremely preterm infants. The changes in ventilation over time and optimal ventilatory management remains unknown. Newer, non-invasive technologies provide insight into these patterns.

Methods

This single-center prospective cohort study enrolled infants ≤32 0/7 weeks. We obtained epochs of transcutaneous carbon dioxide (TcCO₂) measurements twice each week to describe the pattern of hypercarbia throughout their hospitalization.

Results

Patterns of hypercarbia varied based on birth gestational age and post-menstrual age (PMA) (p = 0.03), regardless of respiratory support. Infants receiving the most respiratory support had values 16-21 mmHg higher than those on room air (p < 0.001). Infants born at the youn

SUBMITTER: Sullivan KP 

PROVIDER: S-EPMC7814526 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature