The immune response of T cells and therapeutic targets related to regulating the levels of T helper cells after ischaemic stroke.

ABSTRACT: Through considerable effort in research and clinical studies, the immune system has been identified as a participant in the onset and progression of brain injury after ischaemic stroke. Due to the involvement of all types of immune cells, the roles of the immune system in stroke pathology and associated effects are complicated. Past research concentrated on the functions of monocytes and neutrophils in the pathogenesis of ischaemic stroke and tried to demonstrate the mechanisms of tissue injury and protection involving these immune cells. Within the past several years, an increasing number of studies have elucidated the vital functions of T cells in the innate and adaptive immune responses in both the acute and chronic phases of ischaemic stroke. Recently, the phenotypes of T cells with pr

SUBMITTER: Lei TY 

PROVIDER: S-EPMC7814595 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature