Oral sedation for pain with cervical dilator placement: a randomized controlled trial.

ABSTRACT:

Objective

Assess oral sedation versus placebo for pain control with cervical dilator placement.

Study design

We randomized participants presenting for dilation and evacuation to lorazepam 1 mg/oxycodone 5 mg or placebo 45 min before cervical dilator placement. Our primary outcome was median visual analog scale (VAS) pain score after dilator placement using a 100-mm VAS. We used our outcome data to calculate median pain score changes from baseline to better reflect pain score differences between study groups. Planned sample size was 30 participants per group, for a total of 60.

Results

We randomized 27 participants; 9 received sedation and 11 placebo. Median pain score increase from baseline to last dilator placement was 20 [interquartile range (IQR) 8-29] and 31 (IQR

SUBMITTER: Lee JK 

PROVIDER: S-EPMC7815458 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature