Sex and freezing of gait in Parkinson's disease: a systematic review and meta-analysis.

ABSTRACT:

Objective

It is unknown how sex affects the prevalence of freezing of gait (FOG). We conducted a systematic review and meta-analysis to establish the sex-specific prevalence of FOG in persons with Parkinson's disease (PD). In addition, we investigated whether men and women were represented accurately in intervention trials targeting FOG.

Methods

We queried the EMBASE and PubMed databases and identified 2637 articles. Of these, 16 epidemiological studies were included in the meta-analysis, and 51 intervention studies were included in the comparative analysis.

Results

In total, 5702 persons were included in the final meta-analysis of epidemiological studies. The pooled estimate of overall FOG prevalence was 43% [95% CI 33-53%]. We found no difference in FOG prevalence b

SUBMITTER: Tosserams A 

PROVIDER: S-EPMC7815550 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature